Abstract： Entrainer enhancing technology can significantly improve the solanesol separation efficiency of supercritical CO2 extraction. Based on the principles of supercritical CO2 extraction and enhancing effects from entrainer, three influential factors of the solvents including the type, content and addition method on the extraction of solanesol are examined. How the solanesol and entrainer are selectively separated from the extractive is also discussed. By the orthogonal test of extracting solanesol with entrainer enhancing technology, the importance sequence and prominence are analyzed for the influential factors of entrainer content, pressure and temperature. The optimum conditions for the extraction process are obtained: 25 MPa, 40℃, 150 mL of 95% ethanol for 100 g tobacco. A mathematical model is established with which the yield of the optimum extraction rate of solanesol can be predicted in the present study. Under the optimum conditions of the process, the solanesol extraction rate by designed experiments, 81.5%, is consistant with the prediction value, 82.4%
2007, Vol. 7 
