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›› 2009, Vol. 9 ›› Issue (5): 947-952.

• 系统与集成 • 上一篇    下一篇

甘油发酵生产1,3-丙二醇工艺的技术经济性分析

牟晓佳 滕虎 孙亚琴 修志龙   

  1. 大连理工大学环境与生命学院 大连理工大学环境与生命学院生物科学与工程系 大连理工大学环境与生命学院生物科学与工程系 大连理工大学环境与生命学院生物科学与工程系
  • 收稿日期:2009-05-05 修回日期:2009-06-08 出版日期:2009-10-20 发布日期:2009-10-20
  • 通讯作者: 修志龙

Techno-economic Analysis on Bioconversion of Glycerol into 1,3-Propanediol

MOU Xiao-jia TENG Hu SUN Ya-qin XIU Zhi-long   

  1. Department of Bioscience＆Biotechnology, School of Environment＆Biological Science＆Technology, Dalian University of Technology Department of Bioscience and Biotechnology, School of Environmental and Biological Science and Technology, Dalian University of Technology Department of Bioscience and Biotechnology, School of Environmental and Biological Science and Technology, Dalian University of Technology Department of Bioscience and Biotechnology, School of Environmental and Biological Science and Technology, Dalian University of Technology
  • Received:2009-05-05 Revised:2009-06-08 Online:2009-10-20 Published:2009-10-20
  • Contact: XIU Zhi-long

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摘要： 针对甘油生物转化1,3-丙二醇的连续发酵过程，通过发酵和分离过程的模拟与优化，得到不同初始条件下的最大产物浓度、生产强度、1,3-丙二醇得率及整个工艺过程的物耗和能耗，并进行了经济成本核算. 结果表明，提高发酵过程的生产强度未必能带来利润的增长，反而可能导致利润下降；提高1,3-丙二醇的得率有利于增加利润，但得率高于0.68 mol/mol时，利润增长趋缓；敏感性分析显示，甘油成本是影响利润的关键因素，通过联产生物柴油可以降低成本，税后利润提高31%.

关键词: 3-丙二醇, 技术经济, 动力学模型, 流程模拟

Abstract: The continuous bioconversion of glycerol into 1,3-propanediol was analyzed via modeling and optimizing the fermentation and separation process. The highest concentrations, productivities and yields of 1,3-propanediol under various operational conditions were calculated, coupling with the economic evaluation of the cost of energy and materials. The results indicated that the increase in the productivity would not simultaneously bring more profits, but the opposite, the increase in the yield of 1,3-propanediol to glycerol would bring growth to the profit, but this growth became slow once the yield was higher than 0.68 mol/mol. The economic sensitivity showed that the cost of glycerol was the key factor influencing the profit. Through applying the integrated production of biodiesel and 1,3-propanediol, the cost of glycerol could be saved while the retained profit was increased by 31%.

Key words: 3-propanediol, techno-economics, kinetic modeling, process simulation

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