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›› 2005, Vol. 5 ›› Issue (4): 442-445.

• 生化工程专栏 • 上一篇    下一篇

羧酸型离子交换纤维对卡那霉素的吸附

李夏兰,翁连进,陈培钦,蔡婀娜   

  1. 华侨大学生物工程系
  • 出版日期:2005-08-20 发布日期:2005-08-20

Adsorption of Kanamycin on Carboxylic Ion Exchange Fibers

LI Xia-lan,WENG Lian-jin ,CHEN Pei-qin,CAI E-nuo   

  1. Department of Bioengineering,Huaqiao University
  • Online:2005-08-20 Published:2005-08-20

摘要: 测定了羧酸型离子交换纤维吸附卡那霉素的动力学曲线和吸附等温线,并研究了温度、pH值、盐浓度对吸附卡那霉素的影响. 研究结果表明,羧酸型离子交换纤维吸附卡那霉素在10 min达到平衡,其吸附平衡行为可用Langmuir方程描述;在pH 7时,羧酸型离子交换纤维吸附卡那霉素的静态交换容量为最大,可达5.6′104 U/g;羧酸型离子交换纤维吸附卡那霉素随温度变化很小;NaCl的存在使羧酸型离子交换纤维对卡那霉素的交换容量减小;对发酵液中卡那霉素的动态交换容量为5.16′104 U/g,洗脱率为88.1%.

关键词: 离子交换纤维, 吸附, 卡那霉素, 抗菌素

Abstract: Adsorption kinetics and isotherms of kanamycin on carboxylic ion exchange fibers were measured, and the effects of pH, NaCl concentration and temperature on the adsorption were investigated. Results show that the adsorption reaches equilibrium in 10 min and Langmuir isotherm can well describe the adsorption equilibrium. When pH is 7, their static ion-exchange capacity reaches the largest value of 5.6′104 U/g. It decreases sharply with NaCl concentration increase. Temperature has little effect on the adsorption. The dynamic ion-exchange capacity of adsorption of kanamycin fermentation filtrate on carboxylic ion exchange fibers is 5.16′104 U/g, whose 88.1% can be eluted.

Key words: ion exchange fiber, adsorption, kanamycin, antibiotics