Preparation of Molecularly Imprinted Nanoparticles for Erythromycin and Their Adsorption Characteristics
KOU Xing GENG Li-yuan LEI Jian-du MA Guang-hui SU Zhi-guo
State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences National Laboratoru of Biochemical Engineering, Insitute of Process
Engineering
National Laboratoru of Biochemical Engineering, Insitute of Process
Engineering
National Laboratoru of Biochemical State Key Lab. Biochem. Eng., Inst. Process Eng., Chinese Academy of Sciences State Key Lab. Biochem. Eng., Inst. Process Eng., Chinese Academy of Sciences
Abstract:Uniform molecularly imprinted polymer (MIP) nanoparticles for erythromycin (EM) were prepared by precipitation polymerization using EM as template molecule, methacrylic acid (MAA) as functional monomer and ethylene glycol dimethacrylate (EGDMA) as cross-linker. The synthesis conditions of MIP nanoparticles were optimized and the optimum molar ratio of template molecule to functional monomer was obtained as 1:3. The MIP nanoparticles were characterized. Moreover, the actual maximum apparent adsorption capacity of MIP nanoparticles obtained from the binding experiments was 202.12 mg/g, the adsorption kinetics of MIP nanoparticles showed that the adsorption of MIP nanoparticles in adsorption solution would be equilibrium after 200 min. The MIP nanoparticles for EM possessed highly selective adsorption capacity.
寇星 耿立媛 雷建都 马光辉 苏志国. 红霉素分子印迹聚合物纳米微球的制备及其吸附特性[J]. , 2011, 11(3): 481-486.
KOU Xing GENG Li-yuan LEI Jian-du MA Guang-hui SU Zhi-guo. Preparation of Molecularly Imprinted Nanoparticles for Erythromycin and Their Adsorption Characteristics. , 2011, 11(3): 481-486.