Study on Synthesis, Characterization and Antibacterial Activity of Rare Earth Complexes with Water-soluble Chitosan
WU Jin-xiu LI Mei LIU Zhao-gang HU Yan-hong WANG Mi-tang
College of Rare earth, Inner Mongolia University of Science and Technology Inner Mongolia Science and Technology University Material institute Inner Mongolia Science and Technology University Material institute Inner Mongolia Science and Technology University Material institute Inner Mongolia Science and Technology University Material institute
Abstract：Rare earth-chitosan complexes (CS-La, CS-Nd, CS-Sm, CS-Eu and CS-Dy) were prepared by natural water-soluble chitosan (CS) and rare earth ions (La3+, Nd3+, Sm3+, Eu3+ and Dy3+) in aqueous solution at pH value from 4 to 5 under room temperature, and characterized by FT-IR, UV and TG-DTA. The antibacterial activity of rare earth-chitosan complexes, water-soluble chitosan and rare earth nitrate were also examined. The result of antibacterial activity test showed that the five complexes all had selective antibacterial property, and good bacteriostatic effect to Escherichia coli and Staphylococcus aureus. The minimal inhibitory concentration (MIC) of the five bacteria (Escherichia coli, Staphylococcus aureus, Proteus species, Candida albicans, and Pseudomonas aeruginosa) ranged from 120 to 500 μg/mL, less than 800 μg/mL. The antibacterial activity of complexes was superior to that of water-soluble chitosan and rare earth nitrate. The antibacterial property of CS-Sm to Echerichia coli was the best, its MIC 125 μ g/mL. While, that of CS-Nd and CS-Sm to Staphylococcus aureus was the best, and both of the MIC were 120 μg/mL.
吴锦绣 李梅 柳召刚 胡艳宏 王觅堂. 水溶性壳聚糖稀土配合物的合成、表征及其抑菌性研究[J]. , 2012, 12(6): 1038-1042.
WU Jin-xiu LI Mei LIU Zhao-gang HU Yan-hong WANG Mi-tang. Study on Synthesis, Characterization and Antibacterial Activity of Rare Earth Complexes with Water-soluble Chitosan. , 2012, 12(6): 1038-1042.
2012, Vol. 12 
