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›› 2011, Vol. 11 ›› Issue (6): 965-971.

• 反应与分离 • 上一篇    下一篇

溶剂萃取五味子粗提液中的木脂素

周玲 王学魁 肖清贵 沙作良 徐红彬   

  1. 天津科技大学海洋科学与工程学院 天津科技大学海洋科学与工程学院 中国科学院过程工程研究所 天津科技大学海洋学院 中国科学院过程工程研究所绿色过程与工程重点实验室
  • 收稿日期:2011-09-22 修回日期:2011-10-26 出版日期:2011-12-20 发布日期:2011-12-20
  • 通讯作者: 周玲

Solvent Extraction of Lignans from Schisandra Crude Extractive Solution

ZHOU Ling WANG Xue-kui XIAO Qing-gui WANG Tie-feng XU Hong-bin   

  1. Tianjin University Science and Technology Department of Marine Science and Engineering, Tianjin University of Science or Technology Institute of Process Engineering Chinese Academy of Science College of Marine Science and Engineering, Tianjin University of Science & Technology Institute of Process Engineering, Chinese Academy of Sciences
  • Received:2011-09-22 Revised:2011-10-26 Online:2011-12-20 Published:2011-12-20
  • Contact: ZHOU Ling

摘要: 以水蒸气蒸馏提油、超声醇提、减压浓缩后得到的五味子木脂素粗提液为原料,用溶剂萃取法对五味子木脂素进行提取. 选择了合适的萃取溶剂,探讨了石油醚萃取五味子木脂素机理. 结果表明,此萃取过程为分子萃取,过程动力学为扩散控制. 考察了相比、萃取温度、时间、搅拌速度及萃取级数对五味子木脂素萃取率的影响. 在单因素实验的基础上选择萃取温度、萃取时间和搅拌速率为影响因子,用响应面分析法优化五味子木脂素的萃取纯化工艺条件为萃取时间16 min,萃取温度41℃,搅拌速率520 r/min,在此条件下,其萃取率达92.75%. 纯化物中五味子醇甲含量为14.74%,五味子甲素含量为2.52%,五味子乙素含量为8.33%.

关键词: 五味子, 五味子木脂素, 溶剂萃取, 萃取机理, 表面分析

Abstract: To establish the suitable technology of schisandra lignans with solvent extraction, the single factor experiments and surface analysis were adopted to study the effects of such factors as phase ratio, extraction time, temperature and stirring intensity. The best extraction solvent was petroleum ether and the suitable process conditions were phase ratio 4:1 and temperature 41℃, after 16 min extraction, the extraction rate of schisandra lignans was greater than 90%. The purity of total schisandra lignans increased from 1.28% to 25.5% by using the above technique. The extraction mechanism was also analyzed, schisandra lignans were extracted in the form of neutral molecules and the extraction process was controlled by mass transport diffusion.

Key words: Schisandra chinensis, chisandra lignan, solvent extraction, extraction mechanism, surface analysis

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