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›› 2007, Vol. 7 ›› Issue (4): 767-772.

• 生化工程专栏 • 上一篇    下一篇

大孔吸附树脂吸附乳酸及乳酸与谷氨酸的分离

杨鹏波,张晓燕,丛威,王芳,邓利   

  1. 北京化工大学生命科学与技术学院
  • 出版日期:2007-08-20 发布日期:2007-08-20

Adsorption and Separation of Lactic Acid and Glutamic Acid by Macroporous Resin Adsorbents

YANG Peng-bo,ZHANG Xiao-yan,CONG Wei,WANG Fang,DENG Li   

  1. Col.Life Sci.&Technol.，Beijing University of Chemical Technology
  • Online:2007-08-20 Published:2007-08-20

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被引次数

26

摘要： 通过筛选，得到大孔吸附树脂NKA-II，并用其对乳酸进行分离. 测定了该树脂对乳酸与谷氨酸的吸附选择系数，得到了乳酸在NKA-II上的吸附等温线，并对其吸附动力学和动态吸附进行了研究. 结果表明，NKA-II对乳酸和谷氨酸的吸附选择系数KGL=16.19. 该树脂对乳酸的吸附等温线符合Freundlich方程，在26和48℃下的相关系数R2均大于0.99，方程的特征参数n>1，属"优惠吸附". 吸附动力学研究表明，粒内扩散是吸附过程的主要控制步骤，符合Kannan-Sundaram粒内扩散模型，相关系数R2=0.9906，粒内扩散速率常数kp=6.0129 mg×min0.5/g. 动态吸附实验结果表明，乳酸的穿透体积比谷氨酸大110.6 mL，故该树脂可以成功地应用于乳酸与谷氨酸的分离.

关键词: 大孔吸附树脂, 乳酸, 吸附, 谷氨酸

Abstract: The macroporous resin adsorbent NKA-II was selected to separate lactic acid from the residual solution of fermentation. Adsorption behavior and selectivity of NKA-II were studied by using static and dynamic adsorption methods, including the static equilibrium adsorption and adsorption thermodynamic properties. The results showed that the adsorbent selectivity coefficient (KGL) of lactic acid and glutamic acid equaled to 16.19. The adsorption data were correlated with Freundlich isotherm equation, and the correlative coefficients (R2) all exceeded 0.99 at 26 and 48℃. Characteristic parameter of this equation n>1. Besides, the kinetics of adsorption of NKA-II was mainly controlled by intra-particle diffusion, and it fit well into the Kannan-Sundaram intra-particle diffusion model. The intra-particle diffusion rate coefficient kp was 6.0129 mg×min0.5/g. Dynamic adsorption results showed that the breakthrough volume of L-lactic acid was 140.6 mL, being 110.6 mL over the breakthrough volume of glutamic acid. So macroporous adsorbent NKA-II could be employed as the sorbent to separate lactic acid and glutamic acid.

Key words: macroporous adsorbent, lactic acid, adsorption behavior, glutamic acid