关键词: 4-氨基吡啶, 绿色评价, 原子经济, 环境因子

Abstract: The green evaluation of different synthesis technologies for preparing 4-aminopyridine was carried out by means of atom utilization efficiency, environment factor and environment quotient and GREENSCOPE methods. Contrasted with the traditional processes such as iron powder reduction and catalytic hydrogenation, the electro-reduction technology has some evident advantages, which can be characterized as simple process, high yield, low production cost, benignity to environment and well sustainable development. The electrochemical technology for reduction of nitro compounds to corresponding amines meets with the trend of green chemistry and the demand of sustainable development, and will have a promising prospect in fine chemical field.

Key words: 4-aminopyridine, green evaluation, atom economy, environment factor